Glycolic Acid Science & Safety
The research behind glycolic acid. Clinical evidence, pH science, safety data, and regulatory guidelines for informed skincare decisions.
Skincare marketing often makes claims that outpace the evidence. This section takes a different approach: every article cites peer-reviewed research and clinical studies so you can understand the actual science behind glycolic acid, not just the marketing copy.
From pH chemistry and free acid value calculations to FDA guidelines and clinical trial data, these guides give you the evidence-based foundation to evaluate products and treatments critically.
Topics in Glycolic Acid Science & Safety
The Science of pH in Skincare
Why pH matters for acid efficacy and skin barrier health
Clinical Research on Glycolic Acid
Key studies, evidence quality, and what the data actually shows
Side Effects, Risks, and Safety
Side effects, contraindications, drug interactions, and safety guidelines
Free Acid Value Explained
What FAV means and why listed % isn't the full story
Frequently Asked Questions
Go Deeper With Interactive Tools
The articles above cite the research - these tools let you work with the underlying data directly.
Research Tracker
Browse 49+ peer-reviewed glycolic acid studies. Filter by study type, search by topic, and read plain-language findings.
Search 49+ peer-reviewed studiesStrength Calculator
Calculate the effective free acid value of any glycolic acid product from its concentration and pH. Understand the true potency behind the label percentage.
See your product's real potencyIngredient Interaction Checker
Check if glycolic acid is safe to combine with your other skincare ingredients. 25 ingredients covered with safety ratings and timing advice.
Check before you layer